1. This is presumably a function of urate 's antioxidant properties. 2. Lesinurad enhances urate excretion by inhibition the tubular re-absorption. 3. They also have a tendency to form urate stones. 4. Broiler chickens with the toxicoinfectious form may also have diarrhea with excess urates . 5. Humans do have a gene for urate oxidase, but it is nonfunctional. 6. It is the product of the oxidation of uric acid by urate oxidase. 7. Lesinurad is an urate transporter inhibitor that has been approved to treat gout. 8. Glomerular filtration only accounts for 10 % to 20 % of urinary urate . 9. Urate stones are especially common after colon resection.10. Dutch scientist Antonie van Leeuwenhoek first described the microscopic appearance of urate crystals in 1679. 
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