1. Osteoblasts are specialized, terminally differentiated products of mesenchymal stem cells.2. The brand new bone created by the osteoblast is called osteoid. 3. When Cbfa 1 activates genes the cells differentiate into mature osteoblasts . 4. Progesterone also assists in thyroid function and bone building by osteoblasts . 5. ALP is released by osteoblasts , the ileum, and the placenta. 6. Overexpression of Notch signaling inhibits bone morphogenetic protein2-induced osteoblast differentiation. 7. In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. 8. The osteoblast creates and repairs new bone by actually building around itself. 9. When the osteoblast becomes trapped, it becomes known as an osteocyte. 10. Osteoblasts give rise to the alveolar bone around the roots of teeth.