1. Drastic personality changes are rarely noted, but disinhibition is common. 2. There is evidence that boldness and disinhibition are genetically distinguishable. 3. Modulation of the ? 2 subunit is associated with anxiolytic activity and disinhibition . 4. Risky sexual behaviour is particularly related to the disinhibition facet of sensation seeking. 5. As Grumbach and others have shown, puberty occurs through a surprising process of disinhibition . 6. Disinhibition is different than loss of control.7. Morphine and opioids relate to inhibitory postsynaptic potentials because they induce disinhibition in dopamine neurons. 8. Alcohol use has been linked to sensation seeking, especially the disinhibition and experience seeking subscales. 9. Disinhibition of the tuberomammillary nucleus is the chief mechanism by which caffeine produces wakefulness-promoting effects.10. The short-term effects sought via recreational use include mild euphoria, hallucinations, and disinhibition . 
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